MipSalus’ proprietary technology platform is based on a well-established technology – Molecular Imprinted Polymers (MIPs).
Molecular Imprinted Polymers (MIPs) is a technology that produces antibody-like binding sites in a synthetic polymer by building the polymer matrix around the ligand (“template”). The binding sites in the polymer can be very specific for the selected template molecule and will recognize the template from other closely related structures.
In short, a solution of the template molecule and selected functional monomers is allowed to form the pre-polymerization solution where the functional monomers organize around the template molecule. Subsequently, polymerization is initiated resulting in a solid polymer with the target molecule embedded as single molecules. The solid polymer is then mechanically down-sized into small particles.
Subsequent washing extracts the template molecules leaving cavities in the MIPs particles, which are complementary to the physical and chemical characteristics of the template molecule. These cavities work as binding sites specific for the template molecule.